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Klotho

Gene
Therapy

The current landscape and path forward

Currently there are no approved gene therapies for longevity on the market. Klotho is one of the most potent genes associated with both longevity and cognitive performance, and has a rich research literature proving its connection to key neuroprotective and longevity enhancing features in mice and other model organisms. Klotho has also been associated with increased IQ and longevity in humans in GWAS studies. Biomonadic is developing a novel process to manufacture Klotho protein and gene therapy plasmids with the goal of elucidating its effect on cognition and longevity through animal studies and clinical trials in humans within the next 2 years.

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